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A new way of using DNA to kill cancer cells could pave the way for a cure, scientists say

A new way of using DNA to kill cancer cells could pave the way for a cure, scientists say

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A new way of using DNA to kill cancer cells could pave the way for a cure, scientists say

  • Scientists at the University of Tokyo may have pioneered a way to use DNA to treat cancer
  • Study author Professor Akimitsu Okamoto says their research is ‘good news’
  • It uses hairpin-shaped, cancer-killing DNA that is injected into cancer cells

A new way of using DNA to kill cancer cells, which could pave the way for a cure for the disease, has been developed by scientists.

Professor Akimitsu Okamoto of the University of Tokyo and an author of the study said the research was “good news” and would open up new options for cancer treatment.

The method targets human cervical cancer and breast cancer-derived cells, as well as malignant melanoma cells in mice.

It uses a pair of cancer-killing hairpin-shaped DNA that is injected into cancer cells.

Professor Akimitsu Okamoto (pictured) of the University of Tokyo has a new way of using DNA to kill cancer cells that could pave the way for a cure, said the research was “good news” and would open up new possibilities for cancer treatment

The method, created by scientists at the University of Tokyo (pictured), targets cervical cancer in humans and cells derived from breast cancer, as well as malignant melanoma cells in mice

The method, created by scientists at the University of Tokyo (pictured), targets cervical cancer in humans and cells derived from breast cancer, as well as malignant melanoma cells in mice

When injected into them, they bind to molecules called microRNAs, which are overproduced in some cancers.

After binding to microRNAs, they unravel and form longer chains of DNA that create an immune response.

The immune system recognizes the overproduced microRNA cells as dangerous, which activates a natural immune response that kills the cancer cells.

The Japanese research team says their method is different from existing ones and could herald a new era of breakthrough in cancer drugs.

Prof. Okamoto said: “The results of this study are good news for doctors, drug discovery researchers and cancer patients, as we believe it will give them new opportunities for drug development and drug policy.”

“We will then pursue drug discovery based on the results of this research and look in detail at the efficacy, toxicity and potential methods of drug administration.”

He added: “We thought that if we could create new drugs that work with a different mechanism of action than conventional drugs, they might be effective against cancers that have so far been incurable.”

The new cancer research uses a hairpin-shaped pair of cancer-killing DNA that is injected into cancer cells

The new cancer research uses a hairpin-shaped pair of cancer-killing DNA that is injected into cancer cells

Unfortunately, cancer is a known health problem and the existing ways to treat it have their limitations, but drugs based on DNA and RNA are expected to help scientists eventually defeat it.

This is because DNA and RNA are vital information-carrying molecules that can control the biological function of cells.

They are expected to transform the future of medicine and help treat other hard-to-treat diseases caused by viruses and genetic diseases.

Using DNA and RNA to treat cancer is difficult because it is difficult to get them to distinguish between cancerous and healthy cells.

This means that the patient’s immune system can be adversely affected if healthy cells are attacked.

However, this was the first time scientists were able to engineer a hairpin-shaped strand of DNA that could activate a natural immune response to target and kill specific cancer cells.

The findings are published in the Journal of the American Chemical Society.


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